An exploration of gut microbiota mechanisms underlying differential efficacy of vitamin D supplementation in children associated with lipid metabolism

This study confirms the widespread occurrence of vitamin D insufficiency or deficiency in children, which is negatively correlated with lipid metabolism. <i>Agathobacter</i> may influence vitamin D absorption and lipid metabolism through the 'other carbohydrate degradation' pathway. Our findings offer more insights for clinical problem-solving and new therapies based on child-gut microbiota interactions.