UHPLC-MS/MS-based plasma untargeted lipidomic analysis in patients with diabetes mellitus combined with hyperuricemia
Patients with combined diabetes mellitus and hyperuricemia have significantly altered lipid metabolites compared to diabetic patients and healthy controls. A total of 31 significantly different lipid molecules were identified, and abnormalities in glycerophospholipid metabolism and glycerolipid metabolism pathways were found in DH patients.
Authors
- Youqiong Xu
- Yusong Zhu
- Qihui Chen (ORCID: https://orcid.org/0000-0002-0944-0470)
- Jie Fang (ORCID: https://orcid.org/0000-0003-1526-7851)
- Xiaoyang Zhang (ORCID: https://orcid.org/0000-0002-8230-2605)
- Xinchao Zhang (ORCID: https://orcid.org/0000-0001-8421-4396)
- Wencan Xu (ORCID: https://orcid.org/0000-0002-9270-6937)
Institutions
- Fujian Medical University (CN)
Publication Details
- Journal
- Frontiers in Molecular Biosciences
- Published
- 2025-11-13
- DOI
- https://doi.org/10.3389/fmolb.2025.1656458
- Primary Topic
- Metabolomics and Mass Spectrometry Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00