Bilateral primary orbital lymphoma with proptosis: A case report

Primary orbital lymphoma is a rare extranodal type of lymphoma. Although lymphomas of the head and neck are uncommon, it is the most common orbital malignancy. Most common type is Non-Hodgkin diffuse large B-cell lymphoma. Clinical manifestations can vary, including gradual progressive proptosis, restricted ocular movement, decreased visual acuity, periorbital edema, and diplopia. We describe a case of bilateral primary orbital lymphoma which presented as fever and weight loss for 3 months with history of bilateral proptosis and eye discharge for 2 months. Clinical examination and radiological imaging were consistent with primary orbital lymphoma and was confirmed on histopathological analysis. Treatment is multidisciplinary and includes surgery, radiotherapy, and chemotherapy.

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Journal
Radiology Case Reports
Published
2025-11-13
DOI
https://doi.org/10.1016/j.radcr.2025.10.039
Primary Topic
Lymphoma Diagnosis and Treatment
Type
article
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article

Bilateral primary orbital lymphoma with proptosis: A case report

Sharada Rai, K Suprasanna, Anika Tiku, Sahana D. Acharya
Radiology Case Reports
Lymphoma Diagnosis and Treatment
article

Bilateral primary orbital lymphoma with proptosis: A case report

Sharada Rai, K Suprasanna, Anika Tiku, Sahana D. Acharya
article en

Abstract

Primary orbital lymphoma is a rare extranodal type of lymphoma. Although lymphomas of the head and neck are uncommon, it is the most common orbital malignancy. Most common type is Non-Hodgkin diffuse large B-cell lymphoma. Clinical manifestations can vary, including gradual progressive proptosis, restricted ocular movement, decreased visual acuity, periorbital edema, and diplopia. We describe a case of bilateral primary orbital lymphoma which presented as fever and weight loss for 3 months with history of bilateral proptosis and eye discharge for 2 months. Clinical examination and radiological imaging were consistent with primary orbital lymphoma and was confirmed on histopathological analysis. Treatment is multidisciplinary and includes surgery, radiotherapy, and chemotherapy.

Radiology Case ReportsVol. 21(2)
Manipal Academy of Higher Education (IN), Kasturba Medical College, Manipal (IN)
Openalex Percentile: Top 53%
Lymphoma Diagnosis and Treatment
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