Moyamoya Disease in an Eight‐Year‐Old Female Child—A Case Report

An eight-year-old girl presented with a first episode of focal seizure and transient loss of consciousness. Brain MRI revealed a large subacute infarct in the left fronto-parieto-temporal region, and MR angiography showed bilateral supraclinoid internal carotid and proximal posterior cerebral artery narrowing with extensive basal collateral formation, consistent with Moyamoya disease. The absence of aneurysm or arteriovenous malformation excluded other vascular anomalies. She was managed with hypertonic saline, intravenous antibiotics, and antiplatelet therapy, followed by stabilization and referral for surgical revascularization. This case underscores the importance of maintaining a high index of suspicion for Moyamoya disease in children presenting with new-onset seizures or stroke-like episodes. Early neuroimaging and multidisciplinary management are essential to prevent further ischemic injury and optimize neurological outcomes.

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Publication Details

Journal
Clinical Case Reports
Published
2025-11-01
DOI
https://doi.org/10.1002/ccr3.71384
Primary Topic
Moyamoya disease diagnosis and treatment
Type
article
Field-Weighted Citation Impact
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Moyamoya Disease in an Eight‐Year‐Old Female Child—A Case Report

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Moyamoya Disease in an Eight‐Year‐Old Female Child—A Case Report

Shuhei Kawade, Betsy Annie Philip, Mihirkumar P Parmar, Disha Thapa, S. Nimmagadda, S Mohammed, Abhisar Rohila
article en

Abstract

An eight-year-old girl presented with a first episode of focal seizure and transient loss of consciousness. Brain MRI revealed a large subacute infarct in the left fronto-parieto-temporal region, and MR angiography showed bilateral supraclinoid internal carotid and proximal posterior cerebral artery narrowing with extensive basal collateral formation, consistent with Moyamoya disease. The absence of aneurysm or arteriovenous malformation excluded other vascular anomalies. She was managed with hypertonic saline, intravenous antibiotics, and antiplatelet therapy, followed by stabilization and referral for surgical revascularization. This case underscores the importance of maintaining a high index of suspicion for Moyamoya disease in children presenting with new-onset seizures or stroke-like episodes. Early neuroimaging and multidisciplinary management are essential to prevent further ischemic injury and optimize neurological outcomes.

Clinical Case ReportsVol. 13(11)
Kerala State Council for Science, Technology and Environment (IN), Gandhi Medical College & Hospital (IN), Government Medical College (IN), Guru Gobind Singh Medical College and Hospital (IN), Gujarat Cancer Society (IN), Gandhi Medical College (IN)
Openalex Percentile: Top 52%
Moyamoya disease diagnosis and treatment
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