Adalimumab as a Potential Therapeutic Option for Metastatic Crohn's Disease With Genital Lesions and Edema: A Case Report

Metastatic Crohn's disease (MCD) is a rare and complex extraintestinal manifestation of Crohn's disease (CD) that often profoundly affects patients' quality of life. This report presents a meticulously detailed case of a 12-year-old Iranian girl with persistent labial swelling and genital lesions, later diagnosed as MCD. The case highlights the diagnostic challenges and successful treatment with adalimumab. The study sheds light on the diagnostic intricacies, therapeutic dilemmas, and limited treatment options associated with MCD, a rare condition. This case study advances our understanding of MCD treatment and paves the way for exploring the promising efficacy of adalimumab in managing this challenging condition.

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Publication Details

Journal
Clinical Case Reports
Published
2025-11-01
DOI
https://doi.org/10.1002/ccr3.71424
Citations
1
Primary Topic
Autoimmune and Inflammatory Disorders
Type
article
Field-Weighted Citation Impact
1.35
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Adalimumab as a Potential Therapeutic Option for Metastatic Crohn's Disease With Genital Lesions and Edema: A Case Report

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1 citations
Clinical Case Reports
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article

Adalimumab as a Potential Therapeutic Option for Metastatic Crohn's Disease With Genital Lesions and Edema: A Case Report

Mohammad Aref Bagherzadeh, Behnaz Darban, Hoda Haghshenas, Maryam Ataollahi, Mehdi Karimi
article en
1 citations

Abstract

Metastatic Crohn's disease (MCD) is a rare and complex extraintestinal manifestation of Crohn's disease (CD) that often profoundly affects patients' quality of life. This report presents a meticulously detailed case of a 12-year-old Iranian girl with persistent labial swelling and genital lesions, later diagnosed as MCD. The case highlights the diagnostic challenges and successful treatment with adalimumab. The study sheds light on the diagnostic intricacies, therapeutic dilemmas, and limited treatment options associated with MCD, a rare condition. This case study advances our understanding of MCD treatment and paves the way for exploring the promising efficacy of adalimumab in managing this challenging condition.

Clinical Case ReportsVol. 13(11)
Shiraz University of Medical Sciences (IR), Jahrom University (IR), Hormozgan University of Medical Sciences (IR), Bogomolets National Medical University (UA)
Openalex Percentile: Top 14%
Autoimmune and Inflammatory Disorders
1.35
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