Adalimumab as a Potential Therapeutic Option for Metastatic Crohn's Disease With Genital Lesions and Edema: A Case Report
Metastatic Crohn's disease (MCD) is a rare and complex extraintestinal manifestation of Crohn's disease (CD) that often profoundly affects patients' quality of life. This report presents a meticulously detailed case of a 12-year-old Iranian girl with persistent labial swelling and genital lesions, later diagnosed as MCD. The case highlights the diagnostic challenges and successful treatment with adalimumab. The study sheds light on the diagnostic intricacies, therapeutic dilemmas, and limited treatment options associated with MCD, a rare condition. This case study advances our understanding of MCD treatment and paves the way for exploring the promising efficacy of adalimumab in managing this challenging condition.
Authors
- Mohammad Aref Bagherzadeh (ORCID: https://orcid.org/0000-0002-7109-4476)
- Behnaz Darban (ORCID: https://orcid.org/0000-0003-0309-4359)
- Hoda Haghshenas (ORCID: https://orcid.org/0000-0002-3684-3988)
- Maryam Ataollahi (ORCID: https://orcid.org/0000-0003-1876-5266)
- Mehdi Karimi (ORCID: https://orcid.org/0009-0006-4388-0214)
Institutions
- Shiraz University of Medical Sciences (IR)
- Jahrom University (IR)
- Hormozgan University of Medical Sciences (IR)
- Bogomolets National Medical University (UA)
Publication Details
- Journal
- Clinical Case Reports
- Published
- 2025-11-01
- DOI
- https://doi.org/10.1002/ccr3.71424
- Citations
- 1
- Primary Topic
- Autoimmune and Inflammatory Disorders
- Type
- article
- Field-Weighted Citation Impact
- 1.35