Synthesis of benzodiazepine-containing polyheterocyclic compounds <i>via</i> C–H bond activation-initiated formal [5 + 2] annulation
A novel synthesis of benzodiazepine-containing polyheterocyclics bearing a synthetically valuable vinyl substituent via C–H bond activation-initiated formal [5 + 2] annulation of 2-(indolin-1-yl)-1 H -benzo[ d ]imidazoles with vinyl-1,3-dioxolan-2-one.
Authors
- Xuesen Fan (ORCID: https://orcid.org/0000-0002-2040-6919)
- Yu Fan (ORCID: https://orcid.org/0000-0001-6958-9915)
- Bin Li (ORCID: https://orcid.org/0000-0003-0932-0177)
- Xinying Zhang (ORCID: https://orcid.org/0000-0002-3416-4623)
- Chenchen Huang (ORCID: https://orcid.org/0000-0001-6385-0043)
Institutions
- Henan Normal University (CN)
Publication Details
- Journal
- Organic Chemistry Frontiers
- Published
- 2025-11-13
- DOI
- https://doi.org/10.1039/d5qo01332a
- Primary Topic
- Synthesis and pharmacology of benzodiazepine derivatives
- Type
- article
- Field-Weighted Citation Impact
- 0.00