Dynamic Changes in Free Triiodothyronine (FT3) and Their Correlation with Hearing Recovery in Sudden Sensorineural Hearing Loss: Clinical Implications
Abnormal thyroid function in SSNHL patients was not associated with the severity of hearing loss. However, dynamic changes in FT3 during treatment showed a significant correlation with therapeutic efficacy, suggesting that monitoring ΔFT3 may have clinical value in prognostic assessment. Nonetheless, this study had a limited sample size, and the potential influence of hormone therapy on thyroid function was not accounted for. Therefore, the role of thyroid hormones in SSNHL warrants further validation through large-scale prospective studies and mechanistic investigations.
Authors
- Xiaowen Zhang (ORCID: https://orcid.org/0000-0001-8398-8920)
- Z.-T. Wang
- Runyue Xia (ORCID: https://orcid.org/0000-0003-4017-4788)
- Tao Fu (ORCID: https://orcid.org/0000-0002-6900-5518)
- Shenling Li
- Kaichun Wu (ORCID: https://orcid.org/0000-0002-0699-9666)
- Qiwen Zheng (ORCID: https://orcid.org/0000-0001-6921-6254)
- Siyu Ren (ORCID: https://orcid.org/0009-0006-9958-713X)
- Qiuying Zhu (ORCID: https://orcid.org/0000-0001-6438-6828)
Institutions
- Qingdao University (CN)
- Qingdao Agricultural University (CN)
- Affiliated Hospital of Qingdao University (CN)
Publication Details
- Journal
- Journal of Otology
- Published
- 2025-10-01
- DOI
- https://doi.org/10.26599/joto.2025.9540042
- Primary Topic
- Hearing, Cochlea, Tinnitus, Genetics
- Type
- article
- Field-Weighted Citation Impact
- 0.00