Successful Single Lung Transplantation in Severe Group III Pulmonary Hypertension

Lung transplant provides a durable long-term option for group III pulmonary hypertension patients. Historically, bilateral lung transplant is the preferred option due to superior long-term survival. This benefit manifests itself after 2 years posttransplantation. Recipient medical urgency and organ availability may blunt the benefits of bilateral lung transplant over single lung transplant, necessitating alternative transplant strategies. We report a patient with group III pulmonary hypertension with clinical deterioration while awaiting double lungs who underwent salvage single lung transplant. The patient demonstrated excellent graft function with pulmonary hypertension resolution, highlighting the beneficial potential role of single lung transplant in this patient group.

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Publication Details

Journal
Annals of Thoracic Surgery Short Reports
Published
2025-11-01
DOI
https://doi.org/10.1016/j.atssr.2025.10.006
Primary Topic
Transplantation: Methods and Outcomes
Type
article
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article

Successful Single Lung Transplantation in Severe Group III Pulmonary Hypertension

Tian Sun, Daniel Laskey, Helena Bugacov, Harish Seethamraju et al.
Annals of Thoracic Surgery Short Reports
Transplantation: Methods and Outcomes
article

Successful Single Lung Transplantation in Severe Group III Pulmonary Hypertension

Tian Sun, Daniel Laskey, Helena Bugacov, Harish Seethamraju, Shubham Gulati, Scott Scheinin, Cristina Cusmai
article en

Abstract

Lung transplant provides a durable long-term option for group III pulmonary hypertension patients. Historically, bilateral lung transplant is the preferred option due to superior long-term survival. This benefit manifests itself after 2 years posttransplantation. Recipient medical urgency and organ availability may blunt the benefits of bilateral lung transplant over single lung transplant, necessitating alternative transplant strategies. We report a patient with group III pulmonary hypertension with clinical deterioration while awaiting double lungs who underwent salvage single lung transplant. The patient demonstrated excellent graft function with pulmonary hypertension resolution, highlighting the beneficial potential role of single lung transplant in this patient group.

Annals of Thoracic Surgery Short Reports
Icahn School of Medicine at Mount Sinai (US)
Openalex Percentile: Top 47%
Transplantation: Methods and Outcomes
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