Epidemiology and Outcomes of Battlefield-Related Penetrating and Closed Traumatic Brain Injuries Compared to Non-Head Injuries: A Retrospective Cohort Study

Patients with pTBIs are critically injured with substantial critical care requirements and morbidity. Between patients with pTBIs and cTBIs, there was not a significant difference in non-CNS infection burden or mortality, but pTBI patients did have longer hospitalization. When compared to severely injured military personnel with non-head injuries using propensity scores and IPTW analysis, sustaining a TBI (penetrating or closed) was not associated with having more non-CNS infections or a longer hospital stay. This may be a result of the high injury severity (median of 26) and relative occurrence of polytrauma in the total population. Patients with TBIs (penetrating or closed) did have a greater risk of mortality compared to patients with non-head injuries.

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Publication Details

Journal
Military Medicine
Published
2025-11-12
DOI
https://doi.org/10.1093/milmed/usaf546
Primary Topic
Traumatic Brain Injury and Neurovascular Disturbances
Type
article
Field-Weighted Citation Impact
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article

Epidemiology and Outcomes of Battlefield-Related Penetrating and Closed Traumatic Brain Injuries Compared to Non-Head Injuries: A Retrospective Cohort Study

Bradley A. Dengler, M Leigh Carson, Caren Stuebe, Viktor Bartanusz et al.
Military Medicine
Traumatic Brain Injury and Neurovascular Disturbances
article

Epidemiology and Outcomes of Battlefield-Related Penetrating and Closed Traumatic Brain Injuries Compared to Non-Head Injuries: A Retrospective Cohort Study

Bradley A. Dengler, M Leigh Carson, Caren Stuebe, Viktor Bartanusz, Faraz Shaikh, Callum Dewar, Melissa Meister, Joseph Yabes, Erica Sercy, Jason H. Boulter, David R. Tribble, Laveta Stewart
article en

Abstract

Patients with pTBIs are critically injured with substantial critical care requirements and morbidity. Between patients with pTBIs and cTBIs, there was not a significant difference in non-CNS infection burden or mortality, but pTBI patients did have longer hospitalization. When compared to severely injured military personnel with non-head injuries using propensity scores and IPTW analysis, sustaining a TBI (penetrating or closed) was not associated with having more non-CNS infections or a longer hospital stay. This may be a result of the high injury severity (median of 26) and relative occurrence of polytrauma in the total population. Patients with TBIs (penetrating or closed) did have a greater risk of mortality compared to patients with non-head injuries.

Military Medicine
Henry M. Jackson Foundation (US), Uniformed Services University of the Health Sciences (US), Walter Reed National Military Medical Center (US), Inova Fairfax Hospital (US), Piedmont Atlanta Hospital (US), Bay Pines VA Healthcare System (US), Joint Base San Antonio (US)
Openalex Percentile: Top 53%
Traumatic Brain Injury and Neurovascular Disturbances
DOIOpen Access PDFOpenAlex
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Epidemiology and Outcomes of Battlefield-Related Penetrating and Closed Traumatic Brain Injuries Compared to Non-Head Injuries: A Retrospective Cohort Study — Bradley A. Dengler, M Leigh Carson, et al. · Military Medicine (2025) | TGRS Research Map | TGRS