The evolving landscape of bispecific antibodies in the treatment of lung cancer

The findings suggest that bsAbs represent a significant advancement in lung cancer treatment, offering new therapeutic strategies to address unmet needs. The development of next-generation bsAbs, including trispecific antibodies and conditional activation platforms, promises enhanced precision and safety. These innovations have the potential to improve outcomes for patients with advanced lung cancer. Future research should focus on optimizing patient selection through biomarker-driven approaches and exploring combination therapies to maximize the benefits of bsAbs.

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Publication Details

Journal
Current Opinion in Oncology
Published
2025-11-07
DOI
https://doi.org/10.1097/cco.0000000000001206
Primary Topic
Monoclonal and Polyclonal Antibodies Research
Type
article
Field-Weighted Citation Impact
0.00
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article

The evolving landscape of bispecific antibodies in the treatment of lung cancer

Fei Zhou, Chang Chang, Xuanhong Jin
Current Opinion in Oncology
Monoclonal and Polyclonal Antibodies Research
article

The evolving landscape of bispecific antibodies in the treatment of lung cancer

Fei Zhou, Chang Chang, Xuanhong Jin
article en

Abstract

The findings suggest that bsAbs represent a significant advancement in lung cancer treatment, offering new therapeutic strategies to address unmet needs. The development of next-generation bsAbs, including trispecific antibodies and conditional activation platforms, promises enhanced precision and safety. These innovations have the potential to improve outcomes for patients with advanced lung cancer. Future research should focus on optimizing patient selection through biomarker-driven approaches and exploring combination therapies to maximize the benefits of bsAbs.

Current Opinion in OncologyVol. 38(1)
Tongji University (CN), Shanghai East Hospital (CN)
Openalex Percentile: Top 51%
Monoclonal and Polyclonal Antibodies Research
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