BrainEffeX: A web app for exploring fMRI effect sizes
Effect size estimation is crucial for power analyses and experimental design, but poses unique challenges in fMRI research due to the complexity of the data and analysis techniques. Here, we introduce an interactive web application for exploring fMRI effect maps (neuroprismlab.shinyapps.io/BrainEffeX). We utilized large fMRI datasets to obtain precise voxel-wise and multivariate effect size estimates from "typical" fMRI study designs: brain-behavior correlation, task vs. rest, and between-group analyses of functional connectivity and task-based activation maps. The app is intentionally designed as a growing resource, and we welcome contributions of large (n > 500) datasets.
Authors
- Hallee Shearer (ORCID: https://orcid.org/0000-0002-4813-3473)
- Joshua Curtiss (ORCID: https://orcid.org/0000-0002-4872-5962)
- Rongtao Jiang (ORCID: https://orcid.org/0000-0003-4657-0079)
- Max Rolison (ORCID: https://orcid.org/0000-0001-9534-3767)
- Saloni Mehta (ORCID: https://orcid.org/0000-0003-1775-4776)
- Chris Camp (ORCID: https://orcid.org/0000-0003-2960-8872)
- Matt Rosenblatt
- Dustin Scheinost (ORCID: https://orcid.org/0000-0002-6301-1167)
- Brendan Adkinson (ORCID: https://orcid.org/0000-0003-3196-8674)
- Stephanie Noble (ORCID: https://orcid.org/0000-0002-4804-5553)
- Link Tejavibulya (ORCID: https://orcid.org/0000-0001-5643-9133)
- Qinghao Liang (ORCID: https://orcid.org/0000-0002-6033-0824)
- Catherine Cahill (ORCID: https://orcid.org/0000-0002-5895-9033)
- Jean Ye
- Thomas E. Nichols (ORCID: https://orcid.org/0000-0002-4516-5103)
- Javid Dadashkarimi (ORCID: https://orcid.org/0000-0002-1905-547X)
- Hannah Peterson (ORCID: https://orcid.org/0000-0002-4716-2715)
- Maya Foster (ORCID: https://orcid.org/0000-0002-1617-1811)
- Iris Cheng
- Alexandra Fischbach (ORCID: https://orcid.org/0000-0002-7927-9176)
- Margaret L. Westwater
- Ashley Humphries
Institutions
- Harvard University (US)
- University of California, Los Angeles (US)
- Yale University (US)
- University of Oxford (GB)
- Massachusetts General Hospital (US)
- Universidad del Noreste (MX)
Publication Details
- Journal
- Aperture Neuro
- Published
- 2025-11-12
- DOI
- https://doi.org/10.52294/001c.146251
- Primary Topic
- Functional Brain Connectivity Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Institute of Mental Health