Safety of penicillamine and trientine in the treatment of Wilson’s disease: An analysis of the FDA Adverse Event Reporting System (FAERS) database
This study reveals the characteristics of AEs and potential associated risks in the clinical application of penicillamine and trientine, emphasizing individualized medication and vigilant monitoring strategies to provide guidance for safe medication use.
Authors
- Shijian Cao
- Hui Zhou (ORCID: https://orcid.org/0000-0001-7332-4936)
- Byung-Hoon Min
- Wenming Yang (ORCID: https://orcid.org/0000-0001-8509-2140)
- Yonghua Chen (ORCID: https://orcid.org/0009-0004-2004-4358)
- Wenjuan Xu
- Xu Kou (ORCID: https://orcid.org/0009-0008-5794-9301)
- Zhuo Zhang (ORCID: https://orcid.org/0000-0002-2918-7783)
- Xinyu Zhu (ORCID: https://orcid.org/0000-0002-5352-9499)
- Xiaoxiao Hou (ORCID: https://orcid.org/0000-0003-2965-0616)
- W. B. Qian (ORCID: https://orcid.org/0009-0001-3200-655X)
- Ziwei Li (ORCID: https://orcid.org/0009-0003-5193-3580)
- Jia Ling
Institutions
- Ministry of Education of the People's Republic of China (CN)
- Anhui University of Traditional Chinese Medicine (CN)
Publication Details
- Journal
- PLoS ONE
- Published
- 2025-11-12
- DOI
- https://doi.org/10.1371/journal.pone.0336721
- Citations
- 1
- Primary Topic
- Trace Elements in Health
- Type
- article
- Field-Weighted Citation Impact
- 1.12
Funders
- National Natural Science Foundation of China