Parkinson’s disease: the follow-up consultation

Parkinson's disease (PD) is a complex condition and the requirements for managing both motor and non-motor symptoms evolve during the disease course. General neurologists following up people with PD should provide information, support and lifestyle advice, such as on exercise, with support from a multidisciplinary team. Levodopa remains the most effective and well-tolerated symptomatic treatment, but dose adjustments and adjunctive dopaminergic therapies can help with motor fluctuations. Clinicians should pay close attention to non-motor symptoms, including neuropsychiatric complications such as impulse-control disorders. The evidence base for managing non-motor symptoms is evolving. Involving the patient in the multidisciplinary follow-up of PD can help in managing symptoms unlikely to respond simply to dopamine replacement, including gait problems, falls and swallowing impairment. Clinicians should be open-minded about the diagnosis during follow-up and consider referring appropriate patients to specialists for device-aided therapies.

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Publication Details

Journal
Practical Neurology
Published
2025-11-12
DOI
https://doi.org/10.1136/pn-2025-004697
Primary Topic
Parkinson's Disease Mechanisms and Treatments
Type
article
Field-Weighted Citation Impact
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article

Parkinson’s disease: the follow-up consultation

Christopher Kobylecki
Practical Neurology
Parkinson's Disease Mechanisms and Treatments
article

Parkinson’s disease: the follow-up consultation

Christopher Kobylecki
article en

Abstract

Parkinson's disease (PD) is a complex condition and the requirements for managing both motor and non-motor symptoms evolve during the disease course. General neurologists following up people with PD should provide information, support and lifestyle advice, such as on exercise, with support from a multidisciplinary team. Levodopa remains the most effective and well-tolerated symptomatic treatment, but dose adjustments and adjunctive dopaminergic therapies can help with motor fluctuations. Clinicians should pay close attention to non-motor symptoms, including neuropsychiatric complications such as impulse-control disorders. The evidence base for managing non-motor symptoms is evolving. Involving the patient in the multidisciplinary follow-up of PD can help in managing symptoms unlikely to respond simply to dopamine replacement, including gait problems, falls and swallowing impairment. Clinicians should be open-minded about the diagnosis during follow-up and consider referring appropriate patients to specialists for device-aided therapies.

Practical Neurology
Manchester Academic Health Science Centre (GB), Salford Royal NHS Foundation Trust (GB), University of Manchester (GB)
Openalex Percentile: Top 53%
Parkinson's Disease Mechanisms and Treatments
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