Unusual Presentation of Nephroblastoma in an Adolescent: A Case of Initial Misdiagnosis as a Renal Abscess

We present the case of a 15-year-old girl who initially had fever, flank pain, and imaging findings consistent with a renal abscess. She was treated with antibiotics and improved clinically, but follow-up imaging showed incomplete resolution. After one year, she developed a recurrence, and a large renal mass was identified. Radical nephrectomy was performed, and histopathology confirmed a nephroblastoma tumor. This unusual presentation demonstrates that recurrent or incompletely resolving renal collections may hide an underlying malignancy. Clinicians should maintain suspicion for neoplastic causes in such scenarios, even in age groups where infection is more likely.

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Publication Details

Journal
Cureus
Published
2025-11-12
DOI
https://doi.org/10.7759/cureus.96687
Primary Topic
Renal and related cancers
Type
article
Field-Weighted Citation Impact
0.00
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article

Unusual Presentation of Nephroblastoma in an Adolescent: A Case of Initial Misdiagnosis as a Renal Abscess

Mohamad Y. Jaber, Walid Alameh
Cureus
Renal and related cancers
article

Unusual Presentation of Nephroblastoma in an Adolescent: A Case of Initial Misdiagnosis as a Renal Abscess

Mohamad Y. Jaber, Walid Alameh
article en

Abstract

We present the case of a 15-year-old girl who initially had fever, flank pain, and imaging findings consistent with a renal abscess. She was treated with antibiotics and improved clinically, but follow-up imaging showed incomplete resolution. After one year, she developed a recurrence, and a large renal mass was identified. Radical nephrectomy was performed, and histopathology confirmed a nephroblastoma tumor. This unusual presentation demonstrates that recurrent or incompletely resolving renal collections may hide an underlying malignancy. Clinicians should maintain suspicion for neoplastic causes in such scenarios, even in age groups where infection is more likely.

CureusVol. 17(11)
Lebanese University (LB), University Medical Center Rizk Hospital (LB)
Openalex Percentile: Top 70%
Renal and related cancers
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Unusual Presentation of Nephroblastoma in an Adolescent: A Case of Initial Misdiagnosis as a Renal Abscess — Mohamad Y. Jaber, Walid Alameh · Cureus (2025) | TGRS Research Map | TGRS