Lost to Follow-Up in Neovascular Age-Related Macular Degeneration: A Systematic Review of Global Trends, Risk Factors, and Clinical Consequences
LTFU in nAMD treatment is common and driven by demographic (age, sex, and race), socioeconomic (income and insurance), and access (distance and caregiver need) factors. Continuous treatment, early response, and structured regimens (e.g., T&E) mitigate dropout risk. Interventions to improve access and personalize support are essential to reduce LTFU and preserve visual outcomes.
Authors
- Andrew C. Chang (ORCID: https://orcid.org/0000-0001-9506-0425)
- Thomas Hong (ORCID: https://orcid.org/0000-0002-2899-8832)
- Kimberly Spooner (ORCID: https://orcid.org/0000-0001-5096-3786)
- Hemal Mehta (ORCID: https://orcid.org/0000-0002-0606-9004)
- James Wong
- Geoffrey Broadhead (ORCID: https://orcid.org/0000-0003-1351-4513)
- Samantha Fraser‐Bell (ORCID: https://orcid.org/0000-0001-5646-9359)
Institutions
- Lions Eye Institute (AU)
- University of Technology Sydney (AU)
- The University of Sydney (AU)
- Royal North Shore Hospital (AU)
- Arthritis Australia (AU)
- Sydney Hospital (AU)
- The George Institute for Global Health (AU)
- Australian Centre for Advanced Computing and Communications (Australia) (AU)
- Retina Clinic (BR)
- Sydney Orthopaedic Research Institute (AU)
- Neuroscience Research Australia (AU)
Publication Details
- Journal
- Ophthalmologica
- Published
- 2025-11-12
- DOI
- https://doi.org/10.1159/000549177
- Primary Topic
- Retinal Diseases and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00