Neoadjuvant chemotherapy followed by surgery versus upfront surgery for intrahepatic cholangiocarcinoma: a systematic review and meta-analysis
Compared with upfront surgery, NAT followed by surgery had better results for resectable and locally advanced ICC. Considering the patients in NAT followed by surgery group had more advanced ICC cases, NAT followed by surgery might be a rationale choice for ICC treatment. Further studies about effective downstage treatments for locally advantage ICC are needed in future.
Authors
- Kezhong Tang (ORCID: https://orcid.org/0000-0001-7844-606X)
- Cuiyun Wu (ORCID: https://orcid.org/0000-0002-7414-2090)
- Qifeng Huang (ORCID: https://orcid.org/0000-0003-1830-0143)
- Yanmo Liu
- Yizhao Zhou (ORCID: https://orcid.org/0000-0002-9749-5227)
Institutions
- Sir Run Run Shaw Hospital (CN)
- Second Affiliated Hospital of Zhejiang University (CN)
Publication Details
- Journal
- BMC Cancer
- Published
- 2025-11-12
- DOI
- https://doi.org/10.1186/s12885-025-15203-8
- Citations
- 2
- Primary Topic
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Type
- article
- Field-Weighted Citation Impact
- 4.01