The landscape of dynamic tumor immunophenotyping on neoadjuvant chemotherapy combined with trastuzumab for the treatment of HER2-positive breast cancer
Our dynamic immunophenotyping can provide prediction of the efficacy for NAC with trastuzumab in HER2-positive BC patients, and provide a basis for the selection of subsequent treatment regimens.
Authors
- Wenxin Qi (ORCID: https://orcid.org/0009-0004-1642-7188)
- Dan Yuan (ORCID: https://orcid.org/0000-0002-9074-8770)
- Xiuru Zhang (ORCID: https://orcid.org/0000-0003-0655-4664)
- Yaru Yang (ORCID: https://orcid.org/0000-0002-3170-3572)
- Yanzhao Li (ORCID: https://orcid.org/0000-0002-3170-0291)
- Yunqing Mu
- Dan Guo
- Xiaoyu Hao (ORCID: https://orcid.org/0000-0003-4115-9475)
- Zining Yu
- Jinyuan Xiao
- Xue He (ORCID: https://orcid.org/0000-0003-4448-5399)
- Changjian Yan
- Weilong Zhang (ORCID: https://orcid.org/0000-0001-7702-9010)
- Yuqi Zhang (ORCID: https://orcid.org/0000-0001-6629-4564)
- Mei Liu (ORCID: https://orcid.org/0000-0002-2165-3516)
- Yan Liu (ORCID: https://orcid.org/0000-0003-4242-4840)
- Min Li (ORCID: https://orcid.org/0000-0003-4728-9983)
- Zijian Zhao (ORCID: https://orcid.org/0000-0002-6140-3423)
- Wei Zhang (ORCID: https://orcid.org/0000-0002-8441-0861)
- Chaoling Wu
- Haotian Jin (ORCID: https://orcid.org/0000-0003-4143-5169)
- Qizhao Long
- Xiaoni Liu (ORCID: https://orcid.org/0009-0003-7085-9320)
Institutions
- Shangrao Normal University (CN)
- Fujian Medical University (CN)
- Jiujiang University (CN)
- Jinan University (CN)
- Peking University (CN)
- Chinese PLA General Hospital (CN)
- Southern University of Science and Technology (CN)
- Beijing Tian Tan Hospital (CN)
- 307th Hospital of Chinese People’s Liberation Army (CN)
- BOE Technology Group (China) (CN)
- Aerospace Center Hospital (CN)
- Gannan Medical University (CN)
- First Affiliated Hospital of Gannan Medical University (CN)
- Second Affiliated Hospital of Fujian Medical University (CN)
- Peking University Third Hospital (CN)
- The 309th Hospital of Chinese People's Liberation Army (CN)
- Chongqing Medical University (CN)
Publication Details
- Journal
- Molecular Cancer
- Published
- 2025-11-12
- DOI
- https://doi.org/10.1186/s12943-025-02483-8
- Citations
- 1
- Primary Topic
- HER2/EGFR in Cancer Research
- Type
- article
- Field-Weighted Citation Impact
- 1.05