Changes in Choriocapillaris Flow Deficits Before and After the Onset of Large Choroidal Hypertransmission Defects in AMD

CCFD values did not increase prior to the onset of hyperTDs with increases in CCFDs detected after their onset. These results suggest that loss of choriocapillaris perfusion did not precede hyperTD formation but may play a role in hyperTD growth.

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Publication Details

Journal
Investigative Ophthalmology & Visual Science
Published
2025-11-12
DOI
https://doi.org/10.1167/iovs.66.14.20
Primary Topic
Retinal Diseases and Treatments
Type
article
Field-Weighted Citation Impact
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article

Changes in Choriocapillaris Flow Deficits Before and After the Onset of Large Choroidal Hypertransmission Defects in AMD

Mengxi Shen, Robert C. O’Brien, Nadia Khalida Waheed, Giovanni Gregori et al.
Investigative Ophthalmology & Visual Science
Retinal Diseases and Treatments
article

Changes in Choriocapillaris Flow Deficits Before and After the Onset of Large Choroidal Hypertransmission Defects in AMD

Mengxi Shen, Robert C. O’Brien, Nadia Khalida Waheed, Giovanni Gregori, Alessandro Berni, Omer Trivizki, Sara Beqiri, Yuxuan Cheng, Maura Di Nicola, Gissel Herrera, Farhan E. Hiya, Omar Badla, Philip J. Rosenfeld, Omar S El-Mulki, Ruikang K. Wang, Hong Pan, James Kastner, Bhagavath Sivathanu Kumar
article en

Abstract

CCFD values did not increase prior to the onset of hyperTDs with increases in CCFDs detected after their onset. These results suggest that loss of choriocapillaris perfusion did not precede hyperTD formation but may play a role in hyperTD growth.

Investigative Ophthalmology & Visual ScienceVol. 66(14)
Tufts University (US), Tufts Medical Center (US), University of Miami (US), Vita-Salute San Raffaele University (IT), Tel Aviv University (IL), University of Washington (US), Istituti di Ricovero e Cura a Carattere Scientifico (IT), Istituto di Ricovero e Cura a Carattere Scientifico San Raffaele (IT)
Openalex Percentile: Top 52%
Retinal Diseases and Treatments
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Changes in Choriocapillaris Flow Deficits Before and After the Onset of Large Choroidal Hypertransmission Defects in AMD — Mengxi Shen, Robert C. O’Brien, et al. · Investigative Ophthalmology & Visual Science (2025) | TGRS Research Map | TGRS