Clinical utility of digital technologies in Parkinson’s disease
Digital health technologies (DHTs) are on the verge of changing treatment of Parkinson's disease (PD). This narrative overview article describes DHTs that are already used or in development, focusing on technologies available in Germany and on their clinical utility. Examples include applications that are primarily used by patients, i.e., tools for patient education and empowerment, but also stand-alone interventions improving clinical outcomes including motor and non-motor symptoms. In Germany, these patient-centered DHTs fall under the HTA framework of digital health applications (DIGA). DHT for telemonitoring, in contrast, are designed to support physicians and other healthcare providers and therefore medical devices. DHT are also used increasingly as exploratory endpoints in trials testing neuroprotective treatments.
Authors
- Christoph Redecker (ORCID: https://orcid.org/0000-0001-7452-0525)
- Jürgen Winkler (ORCID: https://orcid.org/0000-0003-0630-9204)
- Björn Falkenburger (ORCID: https://orcid.org/0000-0002-2387-526X)
- Jochen Klucken (ORCID: https://orcid.org/0000-0001-6645-9437)
- Günter U. Höglinger (ORCID: https://orcid.org/0000-0001-7587-6187)
- Thilo van Eimeren (ORCID: https://orcid.org/0000-0002-6951-2325)
- Monika Pötter‐Nerger (ORCID: https://orcid.org/0000-0001-7680-2147)
- Alessandra Fanciulli (ORCID: https://orcid.org/0000-0002-2854-4179)
- Joseph Claßen (ORCID: https://orcid.org/0000-0001-7182-6967)
Institutions
- Innsbruck Medical University (AT)
- Universität Hamburg (DE)
- Centre Hospitalier de Luxembourg (LU)
- Friedrich-Alexander-Universität Erlangen-Nürnberg (DE)
- University of Luxembourg (LU)
- Universität Innsbruck (AT)
- German Center for Neurodegenerative Diseases (DE)
- LMU Klinikum (DE)
- Munich Cluster for Systems Neurology (DE)
- Klinikum Lippe (DE)
- University Hospital Cologne (DE)
- Technische Universität Dresden (DE)
- Ludwig-Maximilians-Universität München (DE)
- Leipzig University (DE)
Publication Details
- Journal
- Journal of Neural Transmission
- Published
- 2025-11-12
- DOI
- https://doi.org/10.1007/s00702-025-03062-3
- Primary Topic
- Parkinson's Disease Mechanisms and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00