Linaclotide in combination with compound polyethylene glycol powder enhances bowel preparation for colonoscopy in patients aged over 60 years: a multi-center, endoscopist-blind, randomized controlled trial
The bowel preparation efficacy of Lina + 2 L-PEG is comparable to that of 3 L-PEG, yet superior to that of 2 L-PEG. Moreover, Lina + 2 L-PEG is associated with fewer adverse reactions, a lower cost, and a higher willingness to repeat the colonoscopy among patients aged over 60 years.
Authors
- Yamei Ran (ORCID: https://orcid.org/0000-0001-9411-7055)
- Juan Xiao (ORCID: https://orcid.org/0000-0003-1064-0602)
- Wenjing Sun (ORCID: https://orcid.org/0000-0001-7503-8562)
- Wenyan Zhao (ORCID: https://orcid.org/0000-0003-4588-2724)
- Kangqi Wu (ORCID: https://orcid.org/0000-0002-4820-8957)
- Zhongxiao Zhang (ORCID: https://orcid.org/0000-0002-5302-9515)
- Xiang Shu (ORCID: https://orcid.org/0009-0008-1383-1301)
- Mei Dong (ORCID: https://orcid.org/0000-0003-1312-382X)
- Yongmei Peng
- Lishi Zhao
Institutions
- Third People 's Hospital of Chongqing (CN)
- Police General Hospital (TH)
Publication Details
- Journal
- Scandinavian Journal of Gastroenterology
- Published
- 2025-11-12
- DOI
- https://doi.org/10.1080/00365521.2025.2588230
- Primary Topic
- Colorectal Cancer Screening and Detection
- Type
- article
- Field-Weighted Citation Impact
- 0.00