Serum Neurofilament Light Is Associated With Future Disease Activity in Clinically Isolated Syndrome and Early Multiple Sclerosis Only After Non‐Optic Neuritis Onset
sNFL but not sGFAP predicted future clinical and MRI disease activity only in pwNON, potentially suggesting that the prognostic value of sNFL may depend on the type of the first manifestation.
Authors
- Susanna Asseyer (ORCID: https://orcid.org/0000-0001-6289-1791)
- Philipp Klyscz (ORCID: https://orcid.org/0000-0003-0058-2365)
- Patrick Schindler (ORCID: https://orcid.org/0000-0002-8846-121X)
- Jens Kühle (ORCID: https://orcid.org/0000-0002-6963-8892)
- Judith Bellmann–Strobl (ORCID: https://orcid.org/0000-0003-2615-1643)
- Tanja Schmitz‐Hübsch (ORCID: https://orcid.org/0000-0003-4833-5937)
- Tatiana Usnich (ORCID: https://orcid.org/0000-0001-7335-8888)
- Lina Anderhalten
- Klemens Ruprecht
Institutions
- Max Delbrück Center (DE)
- Heidelberg University (DE)
- University Hospital of Basel (CH)
- Humboldt-Universität zu Berlin (DE)
- Department of Biomedicine Basel (CH)
Publication Details
- Journal
- European Journal of Neurology
- Published
- 2025-11-01
- DOI
- https://doi.org/10.1111/ene.70375
- Primary Topic
- Multiple Sclerosis Research Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Children's Research Centre