Efficacy of Warmed Inspired Air for Prevention of Perianesthetic Hypothermia in New Zealand White Rabbits (Oryctolagus cuniculus)

Warmed inspired air circuits have proved to be effective in semiclosed heating modalities in veterinary species such as dogs, cats, and nonhuman primates, and thus, there is a gap in species requiring a nonrebreathing circuit. This study evaluated the efficacy of using warmed inspired air in addition to conductive mattress warming in the prevention of hypothermia in anesthetized rabbits (Oryctolagus cuniculus). Rabbits were divided into 2 groups: conductive warming only (control) or conductive warming and warmed inspired air. Our results showed that the addition of a warmed air anesthesia circuit had a significant positive effect on perianesthetic body temperature, maintaining a higher rectal temperature starting 10 minutes after induction and a higher final rectal temperature after a 45-minute anesthetic procedure. At 20 minutes after induction, the body temperature of the warmed air group was not significantly different from baseline compared with a significant drop from baseline in the control group. Infrared pinnal temperatures did not show a pairwise significance in the effect of heating modality and time; however, a clinically significant difference of 2-3 °F between groups was seen. There were no statistically significant differences between groups for time to full recovery and time to extubation. For procedures using rabbits, the addition of warmed inspired air should be considered a significant refinement that promotes normothermia during anesthesia based on consistent and improved overall body temperatures.