SURG-41. Intraventricular Schwannoma Presenting with Memory Impairment and Full Neurological Recovery After Surgical Resection

Abstract INTRODUCTION Intraventricular schwannomas are exceedingly rare, particularly in the left lateral ventricle. Their clinical presentation is often atypical, making diagnosis challenging. This case highlights an unusual manifestation of intraventricular schwannoma presenting with isolated memory impairment, contributing to the limited literature on such rare entities and emphasizing the importance of considering schwannomas in differential diagnoses of intraventricular tumors. MAIN SYMPTOMS AND CLINICAL FINDINGS A 44-year-old female, Flemish origin was admitted following an episode of transient memory impairment two days prior, without an identifiable trigger. The episode was accompanied by a single episode of vomiting and an isolated peak of fever the day before. No other neurological or systemic symptoms were reported. The patient had a remote history of childhood epilepsy without recurrence since the age of 12. Neurological and systemic examinations were unremarkable. MAIN DIAGNOSES, THERAPEUTIC INTERVENTIONS, AND OUTCOMES Brain MRI demonstrated a mass in the left lateral ventricle with radiological features suggestive of a benign lesion. The electroencephalogram (EEG) showed no abnormalities. Corticosteroid therapy was initiated as a preoperative treatment. The patient underwent a neuronavigation-assisted left parietal craniotomy, followed by total microsurgical excision of the tumor. Histopathological examination confirmed the diagnosis of schwannoma. The postoperative period was uneventful, with full neurological recovery and no persistent memory deficits. CONCLUSION This case highlights the exceptional nature of intraventricular schwannomas, particularly when presenting with isolated memory impairment. Complete surgical excision remains the optimal treatment approach, yielding favorable clinical outcomes. Clinicians should consider schwannomas in the differential diagnosis of atypical intraventricular lesions, even in the absence of classical neurological signs.