RBIO-12. Clinical Experiences using CyberKnife for Large-Volume Meningiomas: Preliminary study

Abstract BACKGROUND This preliminary study evaluates the efficacy and safety of CyberKnife hypofractionated radiosurgery for large-volume meningiomas (≥10cc). METHODS We retrospectively analyzed 18 patients treated between 2010 and 2020 at Gyeongsang National University Hospital. RESULTS Results showed a local tumor control rate of 94.4% and a 5-year overall survival rate of 91.7%. Symptomatic peritumoral edema occurred in 61.1% of patients, with most cases managed conservatively, and 16.7% requiring surgical intervention. CONCLUSION These findings suggest that CyberKnife radiosurgery is a viable option for selected patients with large meningiomas, meriting further research with larger cohorts and extended follow-ups.