LungVisionNet: A Hybrid Deep Learning Model for Chest X-Ray Classification—A Case Study at King Hussein Cancer Center (KHCC)

Early diagnosis and rapid treatment of respiratory abnormalities such as many lung diseases including pneumonia, TB, cancer, and other pulmonary problems depend on accurate and fast classification of chest X-ray images. Delayed diagnosis and insufficient treatment lead to the subjective, labour-intensive, error-prone features of current manual diagnosis systems. To tackle this pressing healthcare issue, this work investigates many deep convolutional neural network (CNN) architectures including VGG16, VGG19, ResNet50, InceptionV3, Xception, DenseNet121, NASNetMobile, and NASNet Large. LungVisionNet (LVNet) is an innovative hybrid model proposed here that combines MobileNetV2 with multilayer perceptron (MLP) layers in a unique way. LungVisionNet outperformed previous models in accuracy 96.91%, recall 97.59%, precision, specificity, F1-score 97.01%, and area under the curve (AUC) measurements according to thorough examination on two publicly available datasets including various chest abnormalities and normal cases exhibited. Comprehensive evaluation with an independent, real-world clinical dataset from King Hussein Cancer Centre (KHCC), which achieved 95.3% accuracy, 95.3% precision, 78.8% recall, 99.1% specificity, and 86.4% F1-score, confirmed the model’s robustness, generalizability, and clinical usefulness. We also created a simple mobile application that lets doctors quickly classify and evaluate chest X-ray images in hospitals, so enhancing clinical integration and practical application and supporting fast decision-making and better patient outcomes.