Preparation and Immunological Efficacy Evaluation of mRNA Vaccines Targeting the Spike Protein of Bovine Coronavirus
Both BCoV S-RBD mRNA vaccines had good immunogenicity, with XBS02 providing better protection. This study supports the optimization and application of BCoV mRNA vaccines and accumulates data for mRNA technology in veterinary practice.
Authors
- Xing Fu (ORCID: https://orcid.org/0000-0001-5419-2691)
- Lixue Zhang (ORCID: https://orcid.org/0000-0003-3430-4988)
- Junli Chen (ORCID: https://orcid.org/0000-0002-0542-9709)
- Shiyi Liu (ORCID: https://orcid.org/0009-0008-3279-6476)
- Jun Xia (ORCID: https://orcid.org/0000-0002-7353-1908)
- Ang Lin (ORCID: https://orcid.org/0000-0001-5662-1576)
- Ping Wang (ORCID: https://orcid.org/0000-0003-2932-0617)
- Yue Li (ORCID: https://orcid.org/0000-0001-8198-9911)
- Xue Han (ORCID: https://orcid.org/0000-0002-5276-8631)
- Haoyu Fan (ORCID: https://orcid.org/0009-0008-6248-887X)
- Wei Du (ORCID: https://orcid.org/0000-0002-3628-3298)
- Lijun Xue (ORCID: https://orcid.org/0000-0002-8823-4703)
- Lulu Huang (ORCID: https://orcid.org/0000-0003-4137-0094)
- Zhen Gong (ORCID: https://orcid.org/0000-0003-0760-1493)
- S. Liu
- Fu Chen (ORCID: https://orcid.org/0009-0000-6183-8593)
- Hangfei Bai
Institutions
- Shihezi University (CN)
- Nanjing Agricultural University (CN)
- China Pharmaceutical University (CN)
- Xinjiang Agricultural University (CN)
- Xinjiang Uygur Autonomous Region Disease Prevention and Control Center (CN)
- Xinjiang Academy of Animal Science (CN)
Publication Details
- Journal
- Vaccines
- Published
- 2025-11-12
- DOI
- https://doi.org/10.3390/vaccines13111155
- Primary Topic
- Animal Virus Infections Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- China Pharmaceutical University