HIV-1 drug resistance among pregnant and breastfeeding mothers and its association with paediatric HIV infections in the Dolutegravir era in Uganda
This high HIVDRM burden highlights the urgent need for routine resistance testing, subtype-specific treatment strategies and improved ART adherence support to reduce mother-to-child-transmission, particularly in women with subtype D infections.
Authors
- Sheila N. Balinda (ORCID: https://orcid.org/0000-0001-8374-3122)
- Isaac Ssewanyana
- Alisen Ayitewala (ORCID: https://orcid.org/0000-0001-6173-4006)
- Edward Nelson Kankaka (ORCID: https://orcid.org/0000-0001-6977-3405)
- Denis Byamukama
- Willy Ssengooba (ORCID: https://orcid.org/0000-0002-1643-110X)
- Bernard Kikaire (ORCID: https://orcid.org/0000-0001-9478-9062)
- Anne Kapaata (ORCID: https://orcid.org/0000-0002-0726-1276)
- Obondo James Sande (ORCID: https://orcid.org/0000-0002-2301-5980)
- Juliet Asio (ORCID: https://orcid.org/0000-0001-6593-4937)
- Irene Andia Biraro (ORCID: https://orcid.org/0000-0002-8303-6046)
- Lydia Nakiyingi (ORCID: https://orcid.org/0000-0001-7263-3198)
- Bernard Sentalo Bagaya
- Harriet Mayanja-Kizza
Institutions
- Johns Hopkins University (US)
- Johns Hopkins Medicine (US)
- Ministry of Health (UG)
- Uganda Blood Transfusion Service (UG)
- Rakai Health Sciences Program (UG)
- Institute for Medical Research (MY)
- Makerere University (UG)
- Uganda Virus Research Institute (UG)
- University of Colorado Denver (US)
Publication Details
- Journal
- Journal of Antimicrobial Chemotherapy
- Published
- 2025-11-12
- DOI
- https://doi.org/10.1093/jac/dkaf411
- Primary Topic
- HIV/AIDS Research and Interventions
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Bill and Melinda Gates Foundation
- Massachusetts General Hospital
- Gilead Sciences