Vitamin B12 Deficiency, Hyperhomocysteinemia, and Diabetes as Metabolic Determinants of Cardiovascular Risk in Mexican Women
Vitamin B12 deficiency and hyperhomocysteinemia are very common among Mexican women and are associated with an increased cardiovascular risk, especially in those aged 40 to 49. The analysis showed that implementing a national vitamin B12 supplementation strategy could be a cost-effective preventive measure, with a benefit-cost ratio ranging from 1.93 in the base case to 2.98 when broader societal savings are taken into account. These findings highlight the potential of targeted nutritional interventions to reduce the burden of cardiovascular disease in women.
Authors
- Manlio F. Márquez (ORCID: https://orcid.org/0000-0001-7294-7330)
- Teresa Shamah‐Levy (ORCID: https://orcid.org/0000-0002-1357-720X)
- Dolores Ramírez-Villalobos (ORCID: https://orcid.org/0000-0002-0625-4648)
- Otilia Perichart‐Perera (ORCID: https://orcid.org/0000-0003-1492-5293)
- Nayeli Macías (ORCID: https://orcid.org/0000-0003-2268-9622)
- Jacqueline Elizabeth Alcalde‐Rabanal (ORCID: https://orcid.org/0000-0002-9172-2302)
- Ismael Campos‐Nonato (ORCID: https://orcid.org/0000-0001-5939-3396)
- Eric Monterrubio‐Flores (ORCID: https://orcid.org/0000-0003-1417-9243)
Institutions
- Instituto Nacional de Perinatología (MX)
- National Institute of Public Health (SI)
- National Institute of Public Health (LA)
- Instituto Nacional de Cardiología (MX)
Publication Details
- Journal
- Nutrients
- Published
- 2025-11-12
- DOI
- https://doi.org/10.3390/nu17223535
- Primary Topic
- Folate and B Vitamins Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00