Bile acids: potential links to overweight/obesity and androgen levels in pubertal girls
BAs are important signaling molecules with roles in metabolic and endocrine function. BMI and TBF were inversely associated with BAs, and two BAs were nominally positively associated with FT in girls across a spectrum of body weights. These results suggest novel biological links between altered BA signaling, overweight/obesity, and androgen production among pubertal girls.
Authors
- Fred B. Lih
- Sheri Denslow
- Natalie D. Shaw (ORCID: https://orcid.org/0000-0002-0847-9170)
- Sofia Malave-Ortiz
- Samantha A. M. McNeley
Institutions
- Maryland Oncology Hematology (US)
- National Institute of Environmental Health Sciences (US)
Publication Details
- Journal
- Frontiers in Endocrinology
- Published
- 2025-11-11
- DOI
- https://doi.org/10.3389/fendo.2025.1695465
- Primary Topic
- Drug Transport and Resistance Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Institutes of Health
- National Center for Research Resources