Multi-omics reveals that NOTCH1 promotes cervical cancer progression and reduces radiosensitivity
This study clarifies NOTCH1's role in promoting cervical cancer progression and reducing radiosensitivity, with has-miR-449a as a negative regulator, providing targets for optimizing cervical cancer radiotherapy.
Authors
- Zhiyuan Xie (ORCID: https://orcid.org/0000-0002-2952-5826)
- Yang Sun (ORCID: https://orcid.org/0000-0002-5739-8641)
- Qingzhen Zhan
- E. Zhang
- Aihua Guo
- Peilin Zhong
- Ting Ye (ORCID: https://orcid.org/0000-0001-8072-0363)
- Zhixiong Su (ORCID: https://orcid.org/0000-0002-3497-2073)
- Huaqin Lin
Institutions
- Fujian Medical University (CN)
- Xiamen University (CN)
- Zhongshan Hospital of Xiamen University (CN)
- Fujian Provincial Hospital (CN)
- Fujian Provincial Cancer Hospital (CN)
- Anyang Tumor Hospital (CN)
- Xiamen University of Technology (CN)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2025-11-11
- DOI
- https://doi.org/10.3389/fimmu.2025.1703032
- Primary Topic
- Cerebrovascular and genetic disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00