CHASERR-CHD2 dynamics in T cell quiescence and its modulation by cyclosporine
Our results position the CHASERR-CHD2 axis as a potential regulator of T cell homeostasis and activation. Furthermore, we propose cyclosporine A as a potential therapeutic strategy for conditions involving CHASERR deficiency.
Authors
- Daria Marakulina (ORCID: https://orcid.org/0000-0001-6928-2438)
- Anna Budkina (ORCID: https://orcid.org/0009-0006-1135-5896)
- Nikita A. Sergeev
- Anatoliy Zubritskiy (ORCID: https://orcid.org/0000-0001-5979-7411)
- Marina Loguinova (ORCID: https://orcid.org/0000-0003-3775-4466)
- Yulia A. Medvedeva (ORCID: https://orcid.org/0000-0002-7587-1666)
Institutions
- Hydrometeorological Research Centre of Russian Federation (RU)
- Bioengineering Center (RU)
- Centre of Advanced Studies (RU)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2025-11-11
- DOI
- https://doi.org/10.3389/fimmu.2025.1652359
- Citations
- 1
- Primary Topic
- Signaling Pathways in Disease
- Type
- article
- Field-Weighted Citation Impact
- 0.81