Management of anaphylaxis

Intramuscular epinephrine rapidly reverses airway edema and shock.[1][1] Current evidence does not support use of antihistamines and corticosteroids to prevent progression of anaphylaxis or biphasic reactions, and their use should not delay epinephrine administration.[2][2] Second-generation H1-

Authors

Samira Jeimy (ORCID: https://orcid.org/0000-0002-3425-1874)
Elissa M. Abrams (ORCID: https://orcid.org/0000-0003-3433-1986)
Peter W. Huan

Institutions

Western University (CA)
Lawson Health Research Institute (CA)
University of British Columbia (CA)
Children's Hospital Research Institute of Manitoba (CA)
ENT and Allergy (US)
University of Manitoba (CA)

Publication Details

Journal: Canadian Medical Association Journal
Published: 2025-11-10
DOI: https://doi.org/10.1503/cmaj.250884
Primary Topic: Food Allergy and Anaphylaxis Research
Type: article
Field-Weighted Citation Impact: 0.00

Funders

Sanofi
L'Oreal USA
Ontario Medical Association
Sanofi Genzyme

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article

Management of anaphylaxis

Samira Jeimy, Elissa M. Abrams, Peter W. Huan

Nov 10, 2025

Canadian Medical Association Journal

Food Allergy and Anaphylaxis Research

article

Management of anaphylaxis

Samira Jeimy, Elissa M. Abrams, Peter W. Huan

November 10, 2025article en

Abstract

Intramuscular epinephrine rapidly reverses airway edema and shock.[1][1] Current evidence does not support use of antihistamines and corticosteroids to prevent progression of anaphylaxis or biphasic reactions, and their use should not delay epinephrine administration.[2][2] Second-generation H1-

Canadian Medical Association JournalVol. 197(38)

Western University (CA), Lawson Health Research Institute (CA), University of British Columbia (CA), Children's Hospital Research Institute of Manitoba (CA), ENT and Allergy (US), University of Manitoba (CA)

Sanofi, L'Oreal USA, Ontario Medical Association, Sanofi Genzyme

Openalex Percentile: Top 57%

Food Allergy and Anaphylaxis Research

DOI Open Access PDF OpenAlex

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Management of anaphylaxis — Samira Jeimy, Elissa M. Abrams, et al. · Canadian Medical Association Journal (2025) | TGRS Research Map | TGRS