Bee venom-derived phospholipase A2 modulates microglial activity to promote antidepressant effects in a menopausal mouse model
These results indicate that bvPLA2 exerts antidepressant-like effects in OVX-induced menopausal depression, potentially through the modulation of neuroinflammation and oxidative stress pathways.
Authors
- Minsook Ye (ORCID: https://orcid.org/0000-0002-7918-7992)
- Insop Shim (ORCID: https://orcid.org/0000-0002-8014-9782)
Institutions
- Kyung Hee University (KR)
Publication Details
- Journal
- Frontiers in Psychiatry
- Published
- 2025-11-12
- DOI
- https://doi.org/10.3389/fpsyt.2025.1694735
- Primary Topic
- Healthcare and Venom Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Research Foundation
- Kyung Hee University
- National Research Foundation of Korea