Polyelectromyography Under Propofol to Differentiate Functional from Idiopathic Dystonia: A Pilot Study
During mild sedation, EMG activity persisted in all ID (100%) and in 9 (90%) FD patients. During deep sedation, EMG activity persisted in 9 (53%) ID patients and was absent in all FD patients (100%) (P = 0.01). During partial recovery of consciousness, EMG activity was present in all (100%) ID and only in 1 (10%) FD patients (P < 0.001). At full recovery, a different muscular activation pattern from baseline was observed in 7 (70%) FD and only in 1 (6%) ID patients (P = 0.001) CONCLUSIONS: EMG silence during deep sedation and partial recovery may serve as a neurophysiological marker of FD. A muscular activation pattern differing from baseline may represent a neurophysiological clue for incongruence © 2025 The Author(s). Movement Disorders published by Wiley Periodicals LLC on behalf of International Parkinson and Movement Disorder Society.
Authors
- Fabio Paio (ORCID: https://orcid.org/0000-0002-6534-9911)
- Carla Carozzi (ORCID: https://orcid.org/0000-0001-6677-1172)
- Roberta Telese (ORCID: https://orcid.org/0000-0001-8099-3142)
- Michèle Tinazzi (ORCID: https://orcid.org/0000-0002-2370-7063)
- Arianna Braccia (ORCID: https://orcid.org/0000-0003-1119-7518)
- Gianfranco Gaudiano (ORCID: https://orcid.org/0009-0004-0229-8493)
- Valentina Leta (ORCID: https://orcid.org/0000-0002-5794-7540)
- Marco Gemma
- Roberto Cilia (ORCID: https://orcid.org/0000-0002-1990-1939)
- M Corradi (ORCID: https://orcid.org/0000-0001-5121-5552)
- Roberto Eleopra (ORCID: https://orcid.org/0000-0002-6035-9715)
- Luigi Romito (ORCID: https://orcid.org/0000-0002-6772-1035)
- Sara Rinaldo (ORCID: https://orcid.org/0000-0002-5945-132X)
- Nico Golfrè Andreasi (ORCID: https://orcid.org/0000-0003-3555-5367)
- Antonio Emanuele Elia (ORCID: https://orcid.org/0000-0002-5917-7578)
- Grazia Devigili (ORCID: https://orcid.org/0000-0001-9688-4231)
- Fabiana Colucci (ORCID: https://orcid.org/0000-0003-1945-8153)
- Amanda Oriana
Institutions
- University of Verona (IT)
- King's College London (GB)
- Fondazione IRCCS Istituto Neurologico Carlo Besta (IT)
Publication Details
- Journal
- Movement Disorders
- Published
- 2025-11-12
- DOI
- https://doi.org/10.1002/mds.70094
- Primary Topic
- Neurological disorders and treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00