Hydnocarpin D‐induced microRNA‐145‐5p down‐regulates <i>SERPINE1</i> and suppresses metastasis in ovarian cancer
We showed that HD inhibits metastasis in ovarian cancer by up-regulating microRNA-145-5p, which targets SERPINE1, inhibiting vitronectin/integrin/FAK signalling.
Authors
- Chenjun Shen
- Guozheng Huang (ORCID: https://orcid.org/0000-0002-5730-9549)
- Maowei Ni
- Jingtao Yuan
- Huajun Zhao (ORCID: https://orcid.org/0000-0001-8643-4261)
- Hang Gao (ORCID: https://orcid.org/0000-0002-3403-1257)
- Jiahui Lu (ORCID: https://orcid.org/0009-0009-1354-2830)
- Zhihui Zhu
- Chenying Jiang
Institutions
- Zhejiang Chinese Medical University (CN)
- Zhejiang Cancer Hospital (CN)
- Cancer Hospital of Chinese Academy of Medical Sciences (CN)
- University of Chinese Academy of Sciences (CN)
- Anhui University of Technology (CN)
Publication Details
- Journal
- British Journal of Pharmacology
- Published
- 2025-11-10
- DOI
- https://doi.org/10.1111/bph.70251
- Primary Topic
- Cell Adhesion Molecules Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00