Isolated Unilateral Ovarian Metastasis from Breast Cancer Demonstrated by 18F-FDG PET/CT

A 49-year-old premenopausal woman with a history of left modified radical mastectomy and axillary lymph node dissection for invasive lobular carcinoma three years ago, underwent <sup>18</sup>F-fluorodeoxyglucose positron emission tomography/computed tomography (<sup>18</sup>F-FDG PET/CT) due to gradually increasing CA15-9 and CEA levels during routine follow-up. Compared with previous <sup>18</sup>F-FDG PET/CT images, the left ovary in the current images showed increased size and radiotracer uptake. Subsequently, total abdominal hysterectomy and bilateral salpingo-oophorectomy were performed, and histopathological evaluation confirmed unilateral metastasis in the left ovary due to primary breast cancer. Although rare, possible isolated ovarian metastasis should be considered in patients with breast cancer who have increased size and radiotracer uptake in ovarian tissue on follow-up <sup>18</sup>F-FDG PET/CT scans.

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Publication Details

Journal
Molecular Imaging and Radionuclide Therapy
Published
2025-11-11
DOI
https://doi.org/10.4274/mirt.galenos.2025.54036
Primary Topic
Ovarian cancer diagnosis and treatment
Type
article
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article

Isolated Unilateral Ovarian Metastasis from Breast Cancer Demonstrated by 18F-FDG PET/CT

Nur Aydınbelge Dizdar, Derya Çayır, Ebru Tatçı, Özlem Özmen
Molecular Imaging and Radionuclide Therapy
Ovarian cancer diagnosis and treatment
article

Isolated Unilateral Ovarian Metastasis from Breast Cancer Demonstrated by 18F-FDG PET/CT

Nur Aydınbelge Dizdar, Derya Çayır, Ebru Tatçı, Özlem Özmen
article en

Abstract

A 49-year-old premenopausal woman with a history of left modified radical mastectomy and axillary lymph node dissection for invasive lobular carcinoma three years ago, underwent <sup>18</sup>F-fluorodeoxyglucose positron emission tomography/computed tomography (<sup>18</sup>F-FDG PET/CT) due to gradually increasing CA15-9 and CEA levels during routine follow-up. Compared with previous <sup>18</sup>F-FDG PET/CT images, the left ovary in the current images showed increased size and radiotracer uptake. Subsequently, total abdominal hysterectomy and bilateral salpingo-oophorectomy were performed, and histopathological evaluation confirmed unilateral metastasis in the left ovary due to primary breast cancer. Although rare, possible isolated ovarian metastasis should be considered in patients with breast cancer who have increased size and radiotracer uptake in ovarian tissue on follow-up <sup>18</sup>F-FDG PET/CT scans.

Molecular Imaging and Radionuclide TherapyVol. 35(1)
University of Health Science (KH), Sağlık Bilimleri Üniversitesi (TR), University of Health Sciences Antigua (AG)
Openalex Percentile: Top 56%
Ovarian cancer diagnosis and treatment
DOIOpen Access PDFOpenAlex
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Isolated Unilateral Ovarian Metastasis from Breast Cancer Demonstrated by 18F-FDG PET/CT — Nur Aydınbelge Dizdar, Derya Çayır, et al. · Molecular Imaging and Radionuclide Therapy (2025) | TGRS Research Map | TGRS