The Biomedical Application of a Multifunctional Silane Coating with GO/Ti ₃ C ₂ Heterojunction in Additive Manufacturing of NiTi Alloys

Abstract Additive manufacturing of NiTi alloys has garnered significant attention in the field of medical implants due to their precision and high‐quality molding, and their prominent mechanical properties. However, NiTi alloy as an implant material still faces critical challenges. Herein, the silane coating is applied on the additive‐manufactured NiTi alloy, and a multifunctional GO/Ti 3 C 2 heterojunction is introduced to enhance its anticorrosion, wear resistance, biocompatibility, and antibacterial properties. The GO/Ti 3 C 2 heterojunction enhances the corrosion resistance and stability of the silane coating through the “labyrinth effect,” and improves the wear resistance of NiTi alloy by establishing a lubricating film. Additionally, GO/Ti 3 C 2 demonstrated excellent biocompatibility and efficient photothermal performance. In vitro experiments show that this coating considerably promoted the growth and proliferation of MC3T3‐E1 cells, with a cell viability of 128%. Moreover, after 10 min of Near‐infrared irradiation (NIR), the antibacterial efficiency of this coating against Escherichia coli ( E. coli ) and Staphylococcus aureus ( S. aureus ) reached 98% and 96%, respectively. Furthermore, the silane/GO/Ti 3 C 2 coating effectively encouraged immune cells to shift toward M2 macrophage polarization in vivo implantation experiment. Overall, the multifunctional silane coating with GO/Ti 3 C 2 heterojunctions has the potential to promote the application of additive manufacturing NiTi alloys in the medical field.