Oxidative Stress and Postoperative Outcomes: An Umbrella Review of Systematic Reviews and Meta-Analyses
The findings were organized into three main clinical domains: (1) infectious complications and impaired healing; (2) cardiovascular and systemic complications; and (3) predictive and prognostic value of OS biomarkers for perioperative risk assessment. This thematic synthesis integrates evidence across different surgical specialties, highlighting consistent mechanistic patterns and key research gaps to inform future investigations and clinical decision-making.
Authors
- Alina Renghea (ORCID: https://orcid.org/0000-0003-3585-1844)
- Miguel Ángel Cuevas‐Budhart (ORCID: https://orcid.org/0000-0002-3379-0147)
- Mercedes Gómez del Pulgar García-Madrid (ORCID: https://orcid.org/0000-0002-0418-2337)
- Ana Isabel Sánchez-Bermúdez
- Iván Cavero‐Redondo (ORCID: https://orcid.org/0000-0003-2617-0430)
- Juan Manuel Gallardo (ORCID: https://orcid.org/0000-0001-8833-4651)
- Almudena Crespo-Cañizares (ORCID: https://orcid.org/0000-0001-7622-4199)
- María Mastel Arniella-Blanco
- Aurora Sobrino-Rodríguez
- María Sánchez-Garre
Institutions
- Mexican Social Security Institute (MX)
- University of Cuenca (EC)
- Universidad Francisco de Vitoria (ES)
- Hospital Universitario Quirónsalud Madrid (ES)
- Hospital Quirónsalud Barcelona (ES)
- Centro Medico Nacional Siglo XXI (MX)
- University of Castilla-La Mancha (ES)
Publication Details
- Journal
- Antioxidants
- Published
- 2025-11-11
- DOI
- https://doi.org/10.3390/antiox14111349
- Primary Topic
- Cardiac, Anesthesia and Surgical Outcomes
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Universidad Francisco de Vitoria