Shared Versus Unique Features of Neural Activation During Cognitive Flexibility Across Restrictive Eating Disorder Presentations
These novel findings identified shared versus unique neural features of sustained and transient control across restrictive ED groups. Heightened dlPFC activation during transient control associated with restraint may represent a transdiagnostic feature shared across restrictive EDs. Alternatively, reduced dlPFC activation during the low-demand, single-task condition in those with typical, but not atypical AN, may reflect a difference in sustained control, with implications for tailoring interventions to distinct restrictive ED presentations.
Authors
- Adrienne L. Romer (ORCID: https://orcid.org/0000-0002-1626-0857)
- David Alperovitz
- Poornima Kumar (ORCID: https://orcid.org/0000-0002-9548-3281)
- Kristin N. Javaras (ORCID: https://orcid.org/0000-0003-0885-2331)
- Meghan Lauze (ORCID: https://orcid.org/0009-0001-5282-8032)
- Jason Scott (ORCID: https://orcid.org/0000-0001-6336-5742)
- Jennifer J. Thomas (ORCID: https://orcid.org/0000-0003-2601-581X)
- Felicia Petterway (ORCID: https://orcid.org/0000-0001-9742-0957)
- Madhusmita Misra (ORCID: https://orcid.org/0000-0002-9405-2981)
- Diego A. Pizzagalli (ORCID: https://orcid.org/0000-0002-7772-1143)
- Lauren Breithaupt (ORCID: https://orcid.org/0000-0002-2439-6519)
- Franziska Plessow (ORCID: https://orcid.org/0000-0002-9721-7817)
- Kamryn T. Eddy (ORCID: https://orcid.org/0000-0002-1586-0930)
- Elizabeth A. Lawson (ORCID: https://orcid.org/0000-0001-8619-3349)
- Lauren Lindman
- Meghan Slattery
- Mia Cravitz
- Sarah Naticchia
- Siddarth Seenivasa
- Zara Poon
Institutions
- Brigham and Women's Hospital (US)
- Kaiser Permanente (US)
- Harvard University (US)
- University of California, San Francisco (US)
- American Academy of Child and Adolescent Psychiatry (US)
- McLean Hospital (US)
- Harvard University Press (US)
- Massachusetts General Hospital (US)
- University of Virginia Medical Center (US)
- Imaging Center (US)
- Mass General Brigham (US)
- University of Virginia (US)
- Virginia Tech (US)
Publication Details
- Journal
- International Journal of Eating Disorders
- Published
- 2025-11-11
- DOI
- https://doi.org/10.1002/eat.24599
- Primary Topic
- Eating Disorders and Behaviors
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Institute of Mental Health