Dystrophin-Deficient Muscular Dystrophy in a Family of Shiba Inu Dogs with a Complex Deletion Encompassing DMD Exon 5
This study adds a new breed to the canine dystrophinopathy spectrum having a ~17 kb deletion that encompasses exon 5 of <i>DMD.</i> This same exon 5 deletion has been identified in human dystrophin-deficient muscular dystrophy patients.
Authors
- G. Diane Shelton (ORCID: https://orcid.org/0000-0002-3332-1359)
- Katie M. Minor (ORCID: https://orcid.org/0000-0002-5472-5088)
- Steven G. Friedenberg (ORCID: https://orcid.org/0000-0002-7510-2322)
- Jonah N. Cullen (ORCID: https://orcid.org/0000-0001-5144-8524)
- Ling T. Guo (ORCID: https://orcid.org/0000-0002-2935-2646)
- Laura Mcleay (ORCID: https://orcid.org/0009-0004-6992-6634)
- Simone Hardinge
Institutions
- University of Minnesota (US)
- University of California San Diego (US)
- TissuPath (AU)
- Animal, Food and Health Sciences (AU)
Publication Details
- Journal
- Genes
- Published
- 2025-11-11
- DOI
- https://doi.org/10.3390/genes16111369
- Primary Topic
- Muscle Physiology and Disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- U.S. Department of Agriculture
- National Institutes of Health
- National Institute of Food and Agriculture