Quantitative Analysis of Gadolinium Deposits in Liver Tissue of Patients After Single or Multiple Gadolinium-based Contrast Agent Application

Our results suggest that after intravenous administration of GBCA, a small fraction of gadolinium is retained in the liver over a time period of at least several weeks. A relationship was observed between Gadolinium retention and the number of GBCA administrations, but not with the cumulative dose and the degree of fatty liver disease.

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Publication Details

Journal
Investigative Radiology
Published
2025-11-11
DOI
https://doi.org/10.1097/rli.0000000000001254
Primary Topic
Lanthanide and Transition Metal Complexes
Type
article
Field-Weighted Citation Impact
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article

Quantitative Analysis of Gadolinium Deposits in Liver Tissue of Patients After Single or Multiple Gadolinium-based Contrast Agent Application

Carmen Infante‐Duarte, Christian Bayerl, Kai S. Lehmann, Vanessa Proß et al.
Investigative Radiology
Lanthanide and Transition Metal Complexes
article

Quantitative Analysis of Gadolinium Deposits in Liver Tissue of Patients After Single or Multiple Gadolinium-based Contrast Agent Application

Carmen Infante‐Duarte, Christian Bayerl, Kai S. Lehmann, Vanessa Proß, Andreas Schulz, Patrick Asbach, Matthias Taupitz, Dominik Geisel, Heike Traub, Heiko Tzschätzsch, Anja A. Kühl, Rolf Reiter, Jessica Saatz, Mehrgan Shahryari, Dorit Becker
article en

Abstract

Our results suggest that after intravenous administration of GBCA, a small fraction of gadolinium is retained in the liver over a time period of at least several weeks. A relationship was observed between Gadolinium retention and the number of GBCA administrations, but not with the cumulative dose and the degree of fatty liver disease.

Investigative Radiology
Federal Institute For Materials Research and Testing (DE), Max Delbrück Center (DE), Humboldt-Universität zu Berlin (DE), Berlin Institute of Health at Charité - Universitätsmedizin Berlin (DE), Charité - Universitätsmedizin Berlin (DE), Deutsche Forschungsgemeinschaft (DE)
Openalex Percentile: Top 73%
Lanthanide and Transition Metal Complexes
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Quantitative Analysis of Gadolinium Deposits in Liver Tissue of Patients After Single or Multiple Gadolinium-based Contrast Agent Application — Carmen Infante‐Duarte, Christian Bayerl, et al. · Investigative Radiology (2025) | TGRS Research Map | TGRS