Food‐Activated Microneedle Sensor for Real‐Time, Colorimetric Spoilage Monitoring of Pre‐Packaged Food

At a time of growing food insecurity, developing technologies to reduce food waste is critical. An inexpensive, colorimetric spoilage sensor for real-time food product assessment is reported. The sensor is composed of dehydrated gelatin microneedles that exhibit high mechanical integrity in their base state. However, once exposed to fluid-rich food environments, they rapidly transition to a hydrogel sensing state. Food-derived anthocyanins embedded within these microneedles enable pH-based spoilage monitoring. When applied to sealed fish products, these microneedles nondestructively penetrate through the packaging and are rehydrated by the underlying fish matrix. As the product ages, a defined color shift occurs, demonstrating strong correlation with quantitative spoilage markers. When applied to unsealed fish products for rapid testing, the large microneedle sensing interface enables accelerated colorimetric sensing. Finally, successful fresh vs spoiled categorization of smartphone-acquired images of the sensor using machine learning removes readout ambiguity, empowering consumers with independent real-time product monitoring.

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Publication Details

Journal
Advanced Science
Published
2025-11-12
DOI
https://doi.org/10.1002/advs.202512602
Primary Topic
Advancements in Transdermal Drug Delivery
Type
article
Field-Weighted Citation Impact
0.00

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article

Food‐Activated Microneedle Sensor for Real‐Time, Colorimetric Spoilage Monitoring of Pre‐Packaged Food

Roderick Maclachlan, Akansha Prasad, Tohid Fatanat Didar, Shadman Ahmed Khan et al.
Advanced Science
Advancements in Transdermal Drug Delivery
article

Food‐Activated Microneedle Sensor for Real‐Time, Colorimetric Spoilage Monitoring of Pre‐Packaged Food

Roderick Maclachlan, Akansha Prasad, Tohid Fatanat Didar, Shadman Ahmed Khan, Carlos D. M. Filipe, Mohammed Javed
article en

Abstract

At a time of growing food insecurity, developing technologies to reduce food waste is critical. An inexpensive, colorimetric spoilage sensor for real-time food product assessment is reported. The sensor is composed of dehydrated gelatin microneedles that exhibit high mechanical integrity in their base state. However, once exposed to fluid-rich food environments, they rapidly transition to a hydrogel sensing state. Food-derived anthocyanins embedded within these microneedles enable pH-based spoilage monitoring. When applied to sealed fish products, these microneedles nondestructively penetrate through the packaging and are rehydrated by the underlying fish matrix. As the product ages, a defined color shift occurs, demonstrating strong correlation with quantitative spoilage markers. When applied to unsealed fish products for rapid testing, the large microneedle sensing interface enables accelerated colorimetric sensing. Finally, successful fresh vs spoiled categorization of smartphone-acquired images of the sensor using machine learning removes readout ambiguity, empowering consumers with independent real-time product monitoring.

Advanced ScienceVol. 13(6)
University of Guelph (CA), McMaster University (CA)
Canada Research Chairs, Natural Sciences and Engineering Research Council of Canada
Openalex Percentile: Top 73%
Advancements in Transdermal Drug Delivery
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