Children and Adolescents With Localised Non‐Rhabdomyosarcoma Soft Tissue Sarcoma: Results of the CWS‐96 and CWS‐2002P Prospective Trials With Reclassification of the Trial Data Incorporating the Recent Soft Tissue Sarcoma Registry
Complete resection alone is sufficient to cure low-risk NRSTS. Survival was not improved by dose-intensified adjuvant chemotherapy (with/without maintenance treatment). Patients with completely resected high-risk disease may not profit from adjuvant radiotherapy.
Authors
- Semi Harrabi (ORCID: https://orcid.org/0000-0003-1195-7150)
- Thomas Klingebiel (ORCID: https://orcid.org/0000-0001-5726-9092)
- Kristian W. Pajtler (ORCID: https://orcid.org/0000-0002-3562-6121)
- Ruth Lydia Ladenstein (ORCID: https://orcid.org/0000-0001-6548-3873)
- Martin Ebinger (ORCID: https://orcid.org/0000-0002-4229-8058)
- Roland Imle (ORCID: https://orcid.org/0000-0001-9564-6952)
- Sabine Stegmaier (ORCID: https://orcid.org/0000-0001-7281-8811)
- Bernarda Kazanowska (ORCID: https://orcid.org/0000-0002-7198-9122)
- Anton Schönstein (ORCID: https://orcid.org/0000-0001-8683-5452)
- Ines B. Brecht (ORCID: https://orcid.org/0000-0001-7973-3300)
- Jörg Fuchs (ORCID: https://orcid.org/0000-0003-4171-5371)
- Hanna Juntti
- Gustaf Ljungman (ORCID: https://orcid.org/0000-0002-4949-2494)
- Monika Sparber‐Sauer (ORCID: https://orcid.org/0000-0001-9551-2399)
- Amadeus T. Heinz (ORCID: https://orcid.org/0000-0003-3472-9679)
- Ewa Kościelniak (ORCID: https://orcid.org/0000-0002-1519-7569)
- Christian Vokuhl (ORCID: https://orcid.org/0000-0002-4138-4536)
Institutions
- Goethe University Frankfurt (DE)
- Uppsala University Hospital (SE)
- University of Bonn (DE)
- German Cancer Research Center (DE)
- Heidelberg University (DE)
- Oulu University Hospital (FI)
- University Hospital Bonn (DE)
- University Hospital Heidelberg (DE)
- Wroclaw Medical University (PL)
- Heidelberger Institut für Radioonkologie (DE)
- National Center for Tumor Diseases (DE)
- Olgahospital (DE)
- Hopp Children's Cancer Center Heidelberg (DE)
- St Anna Children's Hospital (AT)
- University Children's Hospital Tübingen (DE)
- University Hospital Frankfurt (DE)
- Klinikum Stuttgart (DE)
- University of Tübingen (DE)
Publication Details
- Journal
- Pediatric Blood & Cancer
- Published
- 2025-11-11
- DOI
- https://doi.org/10.1002/pbc.32159
- Primary Topic
- Sarcoma Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Deutsche Forschungsgemeinschaft
- Deutsche Krebshilfe