A comprehensive analysis of female participation in cardiovascular trials involving the WCN investigator network
Despite underrepresentation, female participation in the selected WCN-CVD trials was sufficient to exclude major sex differences in efficacy. Given the limited and heterogeneous trial sample, further disease-specific studies are needed, and greater female inclusion remains essential for equity and safety insights.
Authors
- Marte F. van der Bijl (ORCID: https://orcid.org/0000-0003-1649-2882)
- Yolande Appelman (ORCID: https://orcid.org/0000-0001-5241-7105)
- Iris C.D. Westendorp (ORCID: https://orcid.org/0000-0003-1367-7195)
- Jeanine E. Roeters van Lennep (ORCID: https://orcid.org/0000-0001-6870-9962)
- Astrid Schut (ORCID: https://orcid.org/0000-0001-9397-7109)
- Hester M. den Ruijter (ORCID: https://orcid.org/0000-0001-9762-014X)
- Eric H. Boersma (ORCID: https://orcid.org/0000-0002-2559-7128)
Institutions
- University Medical Center Utrecht (NL)
- Red Cross Hospital (GR)
- Amsterdam Neuroscience (NL)
- Erasmus MC Cancer Institute (NL)
- Amsterdam University Medical Centers (NL)
- Amsterdam UMC Location Vrije Universiteit Amsterdam (NL)
- Erasmus University Rotterdam (NL)
Publication Details
- Journal
- Netherlands Heart Journal
- Published
- 2025-11-12
- DOI
- https://doi.org/10.1007/s12471-025-01999-4
- Citations
- 3
- Primary Topic
- Sex and Gender in Healthcare
- Type
- article
- Field-Weighted Citation Impact
- 5.64