Pharmacological management of endometriosis pain

Endometriosis is a chronic, neuro-inflammatory disease that occurs when endometrial tissue, normally confined to the uterus, spreads to other areas within the pelvic cavity and beyond. When severe, it can invade the abdominal, peritoneal and thoracic cavity. It is estimated to affect up to 10% of reproductive-aged women, causing debilitating pain, affecting daily activities and can have a significant adverse effect on quality of life. This review describes the presentation and associated symptom of endometriosis before considering current treatment modalities, both pharmacological and non-pharmacological.