The association between parental postpartum depression and offspring autism spectrum disorder
Parental PPD was associated with an increased risk of ASD in the offspring, and this association was partially, though not fully, explained by depression history, antidepressant use, and other parental psychiatric factors. The magnitude of the association increased comparably when either parent was diagnosed with PPD and increased further when both parents were diagnosed, with a pattern indicative of shared genetic influences.
Authors
- Sven Sandin (ORCID: https://orcid.org/0000-0001-6994-4884)
- Michael E. Silverman (ORCID: https://orcid.org/0000-0002-1297-2865)
- Weiyao Yin (ORCID: https://orcid.org/0000-0002-9534-8207)
- Abraham Reichenberg (ORCID: https://orcid.org/0000-0003-2729-8575)
Institutions
- Karolinska Institutet (SE)
- Icahn School of Medicine at Mount Sinai (US)
Publication Details
- Journal
- Frontiers in Psychiatry
- Published
- 2025-11-11
- DOI
- https://doi.org/10.3389/fpsyt.2025.1693979
- Primary Topic
- Family and Disability Support Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Vetenskapsrådet
- National Institutes of Health
- National Institute of Child Health and Human Development
- Eunice Kennedy Shriver National Institute of Child Health and Human Development