Causal relationships between blood metabolites and glioblastoma risk: a large-scale Mendelian randomization study
This study represents the first large-scale Mendelian randomization analysis to establish causal relationships between multiple blood metabolites and glioblastoma risk, particularly identifying protective factors within phospholipid and tryptophan metabolic pathways.
Authors
- Lin Huang (ORCID: https://orcid.org/0000-0003-4753-3683)
- Yali Tan
- Yazhou Tang
- Yongjie Luo (ORCID: https://orcid.org/0009-0003-3754-4300)
- Yuan Wang (ORCID: https://orcid.org/0000-0003-1439-5288)
- Lei Wei (ORCID: https://orcid.org/0000-0001-5140-0504)
Institutions
- Affiliated Hospital of Southwest Medical University (CN)
- Jiangxi Provincial People's Hospital (CN)
- Sichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital (CN)
- Zigong First People's Hospital (CN)
- Second People’s Hospital of Yibin (CN)
Publication Details
- Journal
- Discover Oncology
- Published
- 2025-11-12
- DOI
- https://doi.org/10.1007/s12672-025-03619-4
- Citations
- 1
- Primary Topic
- Metabolomics and Mass Spectrometry Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.81
Funders
- Department of Science and Technology of Sichuan Province