Protamine Utilization and Clinical Outcomes for Coronary Artery Perforation in Chronic Total Occlusion Percutaneous Coronary Intervention Procedures
In this retrospective analysis, use of protamine in patients with coronary artery perforation complicating CTO PCI was associated with a reduction in death and cardiac tamponade without evidence of increased stent thrombosis. Additional studies are warranted to establish optimal strategies for protamine use.
Authors
- Jacob A. Doll (ORCID: https://orcid.org/0000-0002-1459-0262)
- Charles Maynard (ORCID: https://orcid.org/0000-0002-1644-7814)
- Akash Kataruka (ORCID: https://orcid.org/0000-0002-2977-032X)
- David Daniels
- Mahmoud Ahmed (ORCID: https://orcid.org/0000-0003-4720-3588)
- Ravi S. Hira (ORCID: https://orcid.org/0000-0002-6098-0384)
- Kathleen E. Kearney (ORCID: https://orcid.org/0000-0002-1360-9216)
- James M. McCabe (ORCID: https://orcid.org/0000-0003-0452-2327)
- Kanwar Parhar (ORCID: https://orcid.org/0009-0006-3515-7405)
- William Lombardi
Institutions
- MultiCare Health System (US)
- Washington State University Spokane (US)
- University of Washington (US)
- VA Puget Sound Health Care System (US)
- Palo Alto Institute (US)
- Foundation for Health Care Quality (US)
- Georgia Highlands College (US)
Publication Details
- Journal
- Journal of the Society for Cardiovascular Angiography & Interventions
- Published
- 2025-11-11
- DOI
- https://doi.org/10.1016/j.jscai.2025.104000
- Citations
- 1
- Primary Topic
- Coronary Interventions and Diagnostics
- Type
- article
- Field-Weighted Citation Impact
- 2.01