Reversal of third-degree AV block with ruxolitinib in VEXAS-associated myocarditis: a case report
Targeted immunomodulation can reverse cardiac conduction block caused by inflammation in VEXAS syndrome. This case underscores the importance of recognizing autoinflammatory syndromes as a cause of heart block and suggests a potential role for JAK inhibitors in treating inflammatory myocarditis.
Authors
- Jan van Beveren
- Saif Younas (ORCID: https://orcid.org/0000-0001-9808-0093)
- Joris Ector (ORCID: https://orcid.org/0000-0002-1460-7837)
- Jan Bogaert (ORCID: https://orcid.org/0000-0001-7495-9183)
- M. Beckers (ORCID: https://orcid.org/0000-0001-7010-0427)
Institutions
- KU Leuven (BE)
Publication Details
- Journal
- European Heart Journal - Case Reports
- Published
- 2025-11-09
- DOI
- https://doi.org/10.1093/ehjcr/ytaf580
- Primary Topic
- Otitis Media and Relapsing Polychondritis
- Type
- article
- Field-Weighted Citation Impact
- 0.00