The impact of supplementation with iso-branched chain fatty acids in a mouse model of atherosclerosis

Dietary iso-BCFA supplementation may modulate lipid metabolism in ApoE<sup>-/-</sup>/Ldlr<sup>⁻/⁻</sup>mice. The reduction in triglycerides and TC suggests a potential antiatherosclerosis effects, whereas increased aorta lipid content and eADA activity suggest detrimental effect of BCFA supplementation.

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Publication Details

Journal
Molecular Biology Reports
Published
2025-11-12
DOI
https://doi.org/10.1007/s11033-025-11220-9
Primary Topic
Peroxisome Proliferator-Activated Receptors
Type
article
Field-Weighted Citation Impact
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article

The impact of supplementation with iso-branched chain fatty acids in a mouse model of atherosclerosis

Marta Tomczyk, Adriana Mika, Agata Jędrzejewska, Agata Zwara et al.
Molecular Biology Reports
Peroxisome Proliferator-Activated Receptors
article

The impact of supplementation with iso-branched chain fatty acids in a mouse model of atherosclerosis

Marta Tomczyk, Adriana Mika, Agata Jędrzejewska, Agata Zwara, Tomasz Śledziński, Dorota Olszewska−Słonina
article en

Abstract

Dietary iso-BCFA supplementation may modulate lipid metabolism in ApoE<sup>-/-</sup>/Ldlr<sup>⁻/⁻</sup>mice. The reduction in triglycerides and TC suggests a potential antiatherosclerosis effects, whereas increased aorta lipid content and eADA activity suggest detrimental effect of BCFA supplementation.

Molecular Biology ReportsVol. 53(1)
University of Gdańsk (PL), Gdańsk Medical University (PL)
Openalex Percentile: Top 70%
Peroxisome Proliferator-Activated Receptors
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